By Sarah Owermohle, Erin Banco and Adam Cancryn

The U.S. and the world made a huge bet on Novavax, but manufacturing problems are jeopardizing billions of doses earmarked for poor and middle-income countries.

In wake of report on manufacturing difficulties, the Maryland-based drug firm vowed to file for emergency-use authorization by the end of the year.

The U.S. and the world made a huge bet on Novavax, but manufacturing problems are jeopardizing billions of doses earmarked for poor and middle-income countries.

The prospect of abandoning vaccine patents to allow broad global production has pitted public health advocates against industry.

The prospect of abandoning vaccine patents to allow broad global production has pitted public health advocates against industry.

Nancy Messonnier is no longer the head of the agency’s vaccine task force.

Nancy Messonnier is no longer the head of the agency’s vaccine task force.

Nancy Messonnier is no longer the head of the agency’s vaccine task force.

Few others cast as long a shadow as Fauci — who over the past year has given America a crash course in epidemiology — especially with top health posts vacant.

Few others cast as long a shadow as Fauci — who over the past year has given America a crash course in epidemiology — especially with top health posts vacant.

Few others cast as long a shadow as Fauci — who over the past year has given America a crash course in epidemiology — especially with top health posts vacant.

Few others cast as long a shadow as Fauci — who over the last year has given America a crash course in epidemiology — especially with top health posts vacant.

Few others cast as long a shadow as Fauci — who over the last year has given America a crash course in epidemiology — especially with top health posts vacant.